Yu Sleep Ingredients: All Ten, With the Amount in Each Serving and What the Research Says

Yu Sleep is a liquid blend of ten ingredients, taken as 2 mL (two droppers) per serving. This guide lists all ten, in the order the Supplement Facts panel shows them, with the amount the label discloses or, where it does not, the most that amount could be under US labeling rules. Each entry links to our full guide on that ingredient’s research.

It is not medical advice, and it is not a recommendation to take any of these.

The Short Answer

• The label discloses exact amounts for three ingredients: melatonin (0.9 mg), vitamin B2 (0.5 mg) and vitamin B6 (0.5 mg).
• The other seven share one 637 mg “proprietary blend” with no individual amounts. US labeling rules require blend ingredients to be listed from most to least by weight, so a reader can work out a ceiling for each, not the real amount.
• Two of the ten have independent research showing a small average effect on sleep: melatonin, more consistently, and L-theanine, more modestly.
• For five of the ten, we found little to no human trial evidence specific to sleep: GABA, 5-HTP, apigenin, lemon balm and tart cherry each have some research, detailed in the linked guides, but none of it is strong.
• None of the ten has a chronic-insomnia recommendation from a clinical guideline.

Yu Sleep's label ceiling vs. the doses used in trials

Most Yu Sleep's label allowsDose used in the trials

• L-theanineup to 106 mg · trials 200–450 mg
• Magnesium (elemental)up to 45 mg · trial 250 mg
• Lemon balmup to 159 mg · trial 400 mg
• GABAup to 91 mg · trials 75–300 mg

0150300450 mg

Ceilings are worked out from the label order of Yu Sleep's 637 mg blend; the real amounts may be lower. The lemon balm trial used a different preparation. Melatonin (0.9 mg), B6 and B2 (0.5 mg each) are disclosed on the label; tart cherry, apigenin and 5-HTP have no trial dose to compare.

The Ten Ingredients, in Label Order

1. Red tart cherry juice concentrate: no ceiling from the label

Listed first in the blend, so the labeling rule gives it no ceiling below the full 637 mg. A concentrate is also not the same thing as the 240 mL of juice used in the trials below, so there is no clean number to compare. Small early trials found some positive effects on sleep measures, but the two newest placebo-controlled trials we read found no effect. Full evidence: tart cherry for sleep.

2. Magnesium glycinate: at most about 318 mg (about 45 mg of elemental magnesium)

A 2026 review of 12 trials rated the evidence low to very low certainty and does not support routine use for insomnia. The one trial of magnesium bisglycinate that found a small effect used 250 mg of elemental magnesium a day, well above Yu Sleep’s ceiling of about 45 mg. Full evidence: magnesium glycinate for sleep.

3. Apigenin: at most about 212 mg

We found no human trial of apigenin taken alone, so there is no dose to compare the ceiling with. The sedative-like effects reported come from mice and rats; chamomile trials, where apigenin is one of many compounds, gave mixed results. Full evidence: apigenin for sleep.

4. Lemon balm extract: at most about 159 mg

That ceiling is below the 400 mg used in a phytosome trial, though the preparations are not the same. The sleep evidence is small trials, several of them testing lemon balm as part of a combination with other ingredients, not alone. A placebo-controlled trial of one such combination found no benefit, and results depend on the specific preparation used. Full evidence: lemon balm for sleep.

5. 5-HTP (from Griffonia seed extract): at most about 127 mg

We found no placebo-controlled trial of 5-HTP alone in adults with insomnia, so there is no efficacy dose to compare the ceiling with. That ceiling is, however, above the 100 mg at which a toxicology review reports nausea and vomiting. The main published concerns are about safety: interactions with medicines that affect serotonin, and a contested contamination history in some 5-HTP preparations. Full evidence: 5-HTP for sleep.

6. L-theanine: at most about 106 mg

That ceiling is below the 200 to 450 mg range used in the sleep studies. Pooled analyses find small improvements in self-reported sleep, with wide uncertainty, and inconsistent effects on anxiety. A good deal of the underlying research is tied to a maker of the ingredient. Full evidence: L-theanine for sleep.

7. GABA: at most about 91 mg

That ceiling sits above the 75 mg used in the newest trial and below the 100 mg and 300 mg used in older ones. The best pooled review found limited evidence for stress and very limited evidence for sleep. The few sleep trials were small and mostly found only a shorter time to fall asleep. Whether swallowed GABA reaches the brain at all is unsettled. Full evidence: GABA for sleep.

8. Melatonin: 0.9 mg, disclosed

The one ingredient with consistent independent support: pooled trials in people with primary sleep disorders show a small average effect, about 7 minutes faster to fall asleep and 8 minutes more sleep. For chronic insomnia specifically, the American Academy of Sleep Medicine suggests clinicians not use it, a weak recommendation. The case is stronger for jet lag and delayed sleep-wake phase disorder. Independent testing has found the actual melatonin content of supplements ranging from 83% below to 478% above what the label states; we have not tested this product. Full evidence: melatonin for sleep.

9. Vitamin B6 (as pyridoxal-5-phosphate): 0.5 mg, disclosed

We found no trial of B6 alone showing better sleep in adults with insomnia. In one trial, 240 mg of B6 a day, about 480 times Yu Sleep’s amount, increased how much people recalled their dreams and did not significantly change other sleep measures. Full evidence: B vitamins and sleep.

10. Vitamin B2 (as riboflavin-5-phosphate): 0.5 mg, disclosed

Like B6, we found no trial of B2 alone showing better sleep in adults with insomnia. Yu Sleep’s 0.5 mg is about 200 times less than the 100 mg used in one trial that combined vitamins B1 and B2. NIH’s Office of Dietary Supplements says riboflavin has not been shown to cause harm, which is a safety note, not an efficacy finding. Full evidence: B vitamins and sleep.

Why the Ceilings, Not the Real Amounts

US labeling rules require the ingredients inside a “proprietary blend” to be listed in descending order of predominance by weight (21 CFR 101.36(c)(2)). If Yu Sleep’s label follows that rule, each blend ingredient can weigh no more than the remaining blend weight divided by its position, because everything listed ahead of it weighs at least as much. That gives a ceiling, not an amount. Our Yu Sleep review walks through the arithmetic, and our side effects guide uses the same ceilings to check against safety upper limits rather than study doses.

What Is Uncertain

• The real amount of each blend ingredient. Only the ceiling is knowable from the label.
• Whether the label matches the bottle. We are working from the label shown on the maker’s website, not a physical bottle.
• Whether the ten ingredients interact. Every source cited across our guides studies one ingredient at a time. None studies this combination.

Questions

How many ingredients does Yu Sleep have?

Ten: red tart cherry juice concentrate, magnesium glycinate, apigenin, lemon balm extract, 5-HTP, L-theanine, GABA, melatonin, vitamin B6 and vitamin B2.

Which Yu Sleep ingredients have real research behind them?

Melatonin has the most consistent independent support, and L-theanine has modest support. The other eight range from limited evidence to none for sleep specifically, detailed in each ingredient’s linked guide.

How much melatonin is in Yu Sleep?

0.9 mg per 2 mL serving, disclosed on the label.

Why doesn’t the label say how much L-theanine, magnesium or the other blend ingredients Yu Sleep contains?

They are grouped into a 637 mg “proprietary blend,” a labeling category that US rules allow. The rule requires listing the ingredients in order by weight but not disclosing individual amounts.

See Also

Does Yu Sleep Work? weighs the marketed claims against the evidence. Yu Sleep Review covers dose transparency and price. Yu Sleep Side Effects covers safety for each ingredient. For ingredients beyond Yu Sleep’s ten, see the overview of sleep supplements.

Sources Cited in This Guide

1. U.S. Food and Drug Administration. “Dietary Supplement Labeling Guide: Chapter IV. Nutrition Labeling,” and 21 CFR 101.36(c)(2). Read September 19, 2026. FDA guide
2. Yu Sleep Supplement Facts panel, as shown on the maker’s website. Read September 18, 2026. getyusleep.com
3. Per-ingredient sources are listed in full in each linked guide: melatonin, GABA, L-theanine, magnesium glycinate, 5-HTP, apigenin, lemon balm, tart cherry, B vitamins.

This guide is for information and is not medical advice. Talk to a healthcare provider about medication, pregnancy, medical conditions and persistent sleep problems.